The rarest among the rare? Acrometastases and disability in the past and beyond

Abstract Metastatic bone disease significantly impacts cancer‐related morbidity and mortality nowadays. Herein, we present an adult individual, probably a female, with multiple osteolytic lesions, of variable sizes, distributed predominantly in the axial skeleton but also affecting elements appendicular region. This individual exhibits atypical manifestations metastatic disease, form acrometastases—metastases extremities, which are uncommon events current clinical settings. The individual's skeletonized remains were exhumed from crypt Chapel Holy Spirit ( Espírito Santo ), Loures, Portugal, have been dated 16th to 19th centuries. noted both by direct radiological observations, discussed expand knowledge regarding past reflect on disability suffering individuals affected oncologic ailments.